Joint and mobility care plays a central role in ambulation, comfort and overall quality of life. Whether managing chronic joint pain or preparing for a surgical procedure, patients benefit from choosing a center known for advanced technology, experienced specialists and patient-centered care.
This guide highlights some of the best musculoskeletal surgery centers across five U.S. states, including one of the top-rated orthopedic centers in the Houston area of Texas, to help patients make confident and informed decisions.
Methodology for Selecting Orthopedic Centers
To identify today’s leading joint care programs, this list draws from several indicators, including:
- Patient-centered care: Centers known for individualized treatment plans, clear communication and supportive recovery programs rank highest.
- Surgical excellence and outcomes: Strong national rankings, low complication rates and consistent patient satisfaction speak volumes. Facilities with more surgeons also provide greater opportunities, as there were only 19,344 orthopedic surgeons registered in the U.S. in 2023.
- Advanced technology: The use of minimally invasive and robotic-assisted techniques, along with evidence-based treatment models, indicates high proficiency.
- Multidisciplinary approaches: Collaboration among musculoskeletal surgeons, physical therapists, imaging teams, rheumatologists and other specialty clinicians makes for swift recovery.
- Access and convenience: Geographic accessibility, telehealth options and multiple clinic locations increase each brand’s accessibility.
5 Leading Orthopedic Surgery Centers Across the Nation
Discover the treatment and surgical centers that provide world-class joint care surgery and aftercare.
1. Best in Texas: Fondren Orthopedic Group

Fondren Orthopedic Group, a division of OrthoLoneStar, is one of the top-rated orthopedic surgery centers in the Houston area. The group represents one of Texas’s most comprehensive musculoskeletal networks, with more than 40 specialists covering every major subspecialty.
Surgeons utilize state-of-the-art technology, including robotic-assisted systems and minimally invasive approaches, which support shorter recovery times. Fondren’s patient-first model focuses on personalized treatment plans, convenient scheduling options and a collaborative care experience that extends through rehabilitation.
Key features:
- Extensive subspecialty coverage
- Advanced surgical technology and ongoing research
- Multiple clinic and hospital affiliations
2. Best in New York: Hospital for Special Surgery

The Hospital for Special Surgery (HSS) is a global leader in musculoskeletal medicine and consistently earns national recognition for joint care excellence. Patients benefit from its specialization in orthopedics and rheumatology.
The hospital leads research in joint replacement, sports medicine and complex surgical reconstruction, and it operates integrated care teams that guide patients from evaluation through rehabilitation. The facility was founded in 1863 — making it one of the oldest hospitals in the U.S. — but its forward-thinking methodology serves 200,000 patients and thousands of musculoskeletal students each year.
Key features:
- Nation-leading rankings
- Extensive research and teaching portfolio
- Specialized care centers
3. Best in Minnesota: Mayo Clinic

The Mayo Clinic brings together surgeons, physiatrists, radiologists and other specialists to diagnose and treat various mobility conditions.
Its integrated, team-based approach provides patients with complex medical histories coordinated care across departments. The Mayo Clinic’s commitment to evidence-based practice ensures access to the latest clinical trials and regenerative therapies. Its three locations feature over 100 surgeons and doctors in the bone and joint field.
Key features:
- Expertise in complex musculoskeletal cases
- Research-driven environment
- Comprehensive rehabilitation services
4. Best in Illinois: Rush University Medical Center

Rush University Medical Center has earned national recognition for mobility care excellence, especially in joint replacement, spine care and sports medicine. Its specialists treat professional athletes as well as everyday patients seeking long-term mobility solutions. Its innovative research culture influences its surgical methods, rehabilitation strategies and technology adoption.
The institution provides exceptional patient care and is renowned for its expertise in hip replacement. It also helps train the orthopedic minds of the future.
Key features:
- Pioneering minimally invasive techniques
- Strong performance in hip and knee replacement outcomes
- Dedicated spine and back center
5. Best in Ohio: Cleveland Clinic’s Orthopaedic & Rheumatologic Institute

Cleveland Clinic’s Orthopaedic & Rheumatologic Institute delivers high-volume surgical care that drives consistent outcomes in joint replacement, spine procedures and trauma reconstruction.
The institute prioritizes innovation and accessibility, with options such as virtual second opinions, expanded telehealth services and partnerships across the Cleveland Clinic network. Its evidence-based treatment guidelines support long-term functional improvement, and the clinic performs over 7,000 replacement operations annually.
Key features:
- High surgical volume with increased expertise
- Commitment to innovation
- Expanded access options
Comparing the Nation’s Leading Centers at a Glance
To support careful decision-making, this side-by-side view of the centers highlights their unique offerings and service models.
| Fondren Orthopedic Group | Hospital for Special Surgery | Mayo Clinic | Rush University Medical Center | Cleveland Clinic’s Orthopaedic & Rheumatologic Institute | |
| Primary location | Houston, Texas | New York, New York | Rochester, Minnesota | Chicago, Illinois | Cleveland, Ohio |
| Key strength | Comprehensive subspecialty care | Musculoskeletal focus | Integrated multispecialty care | Joint replacement and sports medicine | High surgical volume and innovation |
| Approach | Patient-centered and technology-driven | Research-intensive | Collaborative and holistic | Innovative and outcomes-focused | Evidence-based and accessible |
| Best for | Patients seeking advanced care with convenient Texas access | Complex cases requiring top-ranked specialty care | Patients needing coordinated multispecialty support | Hip and knee replacement and sports injuries | Patients seeking virtual options and broad expertise |
Moving Forward With Confidence
Choosing the right musculoskeletal institute depends on an individual’s specific condition, goals and preferences. The top programs represent excellence in surgical outcomes, advanced technology and coordinated care.
Before scheduling a procedure, verify insurance coverage, prepare relevant medical records and confirm appointment availability with the surgeon of your choice. With the right team and a patient-centered plan, long-term mobility and comfort become realistic, achievable goals.